Индивидуальная гиперчувствительность к компонентам препарата. Тяжелые врожденные или приобретенные нарушения свертываемости крови (гемофилия, тяжелые поражения печени), заболевания, связанные с повышенной вероятностью кровотечений, тромбоцитопения.
Комбинированный препарат. представляет собой комбинацию высокоактивных ферментов растительного и животного происхождения. оказывает иммуномодулирующее, противовоспалительное, фибринолитическое, противоотечное, антиагрегантное и вторичное анальгезирующее действие.вобэнзим оказывает положительное воздействие на ход воспалительного процесса, ограничивает патологические проявления аутоиммунных и иммунокомплексных процессов, положительно влияет на показатели иммунологической реактивности организма. стимулирует и регулирует функциональную активность моноцитов-макрофагов, естественных киллеров, стимулирует противоопухолевый иммунитет, цитотоксические т-лимфоциты, фагоцитарную активность клеток.под воздействием вобэнзима снижается количество циркулирующих иммунных комплексов и происходит выведение мембранных депозитов иммунных комплексов из тканей.вобэнзим уменьшает инфильтрацию интерстиция плазматическими клетками. повышает элиминацию белкового детрита и депозитов фибрина в зоне воспаления, ускоряет лизис токсических продуктов обмена веществ и отмирающих тканей, улучшает рассасывание гематом и отеков, нормализует проницаемость стенок сосудов.вобэнзим снижает концентрацию тромбоксана и агрегацию тромбоцитов. регулирует адгезию клеток крови, повышает способность эритроцитов изменять свою форму, регулируя их пластичность, нормализует число нормальных дискоцитов (тромбоцитов) и уменьшает общее число активированных форм тромбоцитов, нормализует вязкость крови, снижает общее число микроагрегантов, таким образом улучшая микроциркуляцию и реологические свойства крови, а также снабжение тканей кислородом и питательными веществами.вобэнзим нормализует липидный обмен, снижает синтез эндогенного холестерина, повышает содержание лпвп, снижает уровень атерогенных липидов, улучшает всасывание полиненасыщенных жирных кислот.вобэнзим повышает эффективность антибиотикотерапии, увеличивая концентрацию антибиотиков в плазме крови и очаге воспаления, а также уменьшает побочные эффекты антибиотиков (дисбактериоз).вобэнзим уменьшает выраженность побочных эффектов, связанных с приемом гормональных препаратов (в т.ч. гиперкоагуляцию).вобэнзим регулирует механизмы неспецифической защиты (выработка интерферонов), тем самым проявляя противовирусное и противомикробное действие.
Индивидуальная гиперчувствительность к компонентам препарата. Тяжелые врожденные или приобретенные нарушения свертываемости крови (гемофилия, тяжелые поражения печени), заболевания, связанные с повышенной вероятностью кровотечений, тромбоцитопения.
Применение при беременности и в период грудного вскармливания
С осторожностью и под контролем врача следует назначать Вобэнзим при беременности и в период лактации.
Способ применения и дозы
Таблетки следует принимать внутрь, не менее чем за 30 минут до еды, не разжевывая, запивая водой (200 мл).
Взрослые
В зависимости от активности и тяжести заболевания Вобэнзим принимают в дозе от 3 до 10 таблеток 3 раза в день. В первые три дня приема препарата рекомендуемая доза составляет 3 таблетки 3 раза в день.
При средней активности заболевания Вобэнзим назначают в дозе 5-7 таблеток 3 раза в день в течение 2-х недель. В дальнейшем доза Вобэнзима должна быть снижена до 3-5 таблеток 3 раза в день, курс 2 недели.
При высокой активности заболевания Вобэнзим назначают в дозе 7-10 таблеток 3 раза в день в течение 2-3 недель. В дальнейшем, доза Вобэнзима снижается до 5 таблеток 3 раза в день, курс 2-3 месяца.
При хронических длительно текущих заболеваниях Вобэнзим может применяться по показаниям курсами от 3-х до 6-ти месяцев и более.
С целью повышения эффективности антибиотиков и профилактики дисбактериоза, Вобэнзим следует применять на протяжении всего курса антибиотикотерапии в дозе по 5 таблеток 3 раза в день. После прекращения курса антибиотиков для восстановления микрофлоры (биоценоза) кишечника Вобэнзим следует назначать по 3 таблетки 3 раза в день в течение 2-х недель.
В качестве терапии «прикрытия» во время проведения химио- и лучевой терапии, Вобэнзим следует применять в дозе по 5 таблеток 3 раза в день до завершения курса химио- и лучевой терапии; для предупреждения инфекционных осложнений, улучшения переносимости базисной терапии и повышения качества жизни.
При применении Вобэнзима с профилактической целью доза препарата составляет 3 таблетки 3 раза в день, курс 1,5 месяца с повторением 2-3 раза в год.
Дети
Детям с 5-ти до 12 лет - на 6 кг веса ребенка 1 таблетка в сутки. С 12 лет по схеме для взрослых. Дозировка и длительность лечения зависят от тяжести заболевания и определяются врачом.
О случаях передозировки препарата Вобэнзим не сообщалось.
Взаимодействие с другими лекарственными средствами
При одновременном приеме Вобэнзима с другими лекарствами случаи несовместимости не описаны.
Особые указания
Следует учитывать, что в начале лечения препаратом Вобэнзим возможно обострение симптомов заболевания. В таких случаях рекомендуют временно снизить дозу, лечение прерывать не следует. При инфекционно-воспалительных заболеваниях Вобэнзим не заменяет лечения антибиотиками, но повышает их эффективность. Вобэнзим не является допингом. Влияние на способность к вождению автотранспорта и управлению механизмамиПрепарат не оказывает негативного влияния на способность к вождению автомобиля и выполнению работ, требующих высокой скорости психомоторных реакций.
Влияние на способность управлять автомобилем и движущимися механизмами
Препарат не оказывает отрицательного влияния на способность управлять транспортными средствами и выполнять работы, требующие высокой скорости психических и физических реакций.
Форма выпуска
Таблетки кишечнорастворимые, покрытые оболочкой.
По 20 таблеток в ПВХ/ПЭ/ПВДХ/алюминиевые блистеры.
По 2, 5 или 10 блистеров вместе с инструкцией по применению в пачку картонную.
По 800 таблеток во флаконы из полиэтилена высокой плотности. По 1 флакону вместе с инструкцией по применению в пачку картонную.
Условия хранения
При температуре не выше 25 °C.
Хранить в недоступном для детей месте!
Срок годности
2 года.
Не применять по истечении срока годности
Условия отпуска
Отпускают без рецепта.
Производитель
Мукос Эмульсионс ГмбХ, Германия
Мирауштрассе 17, 13509 Берлин, Германия
Организация, принимающая претензии потребителей
За дополнительной информацией обращаться в ООО «Атриум Инновейшенс РУС»:
121059, г. Москва, ул. Киевская, д. 14, стр. 1, офис 011 июня 2018 г.
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Ед. (100,0 мг), папаин 90 FIP Ед. (18,00 мг), рутозида тригидрат 50,00 мг, бромелаин 225 FIP Ед. (45,00 мг), трипсин 360 FIP Ед. (12,00 мг), липаза 34 FIP Ед. (10,00 мг), амилаза 50 FIP Ед. (10,00 мг), химотрипсин 300 FIP Ед. (0,75 мг)."}},{"type":"paragraph","data":{"text":"Вспомогательные вещества:"}},{"type":"paragraph","data":{"text":"Лактозы моногидрат 149 мг, крахмал прежелатинизированный 31,3 мг, магния стеарат 6,00 мг, стеариновая кислота 6,00 мг, кремния диоксид коллоидный безводный 3,00 мг, тальк 1,50 мг."}},{"type":"paragraph","data":{"text":"Оболочка:"}},{"type":"paragraph","data":{"text":"Пленочная оболочка 11,9 мг (сополимер метакриловой кислоты-метилметакрилата (1:1) 11,9 мг, натрия лаурилсульфат 0,04 мг), тальк 4,23 мг, макрогол 6000 0,67 мг, триэтилцитрат 1,20 мг, стеариновая кислота 6,00 мг, цветное покрытие 12,8 мг (гипромеллоза 3,20 мг, гидроксипропилцеллюлоза 3,83 мг, целлюлоза микрокристаллическая 1,60 мг, глицерол 0,64 мг, тальк 1,92 мг, титана диоксид 0,38 мг, краситель пунцовый 4R (Е 124) 0,38 мг, краситель желто-оранжевый S (Е 110) 0,83 мг)."}}]},{"id":12,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"круглые, двояковыпуклые таблетки с гладкой поверхностью, от краснооранжевого до красного цвета, с характерным запахом."}}]},{"id":13,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"противовоспалительное, иммуномодулирующее средство."}}]},{"id":2,"name":"Фармакологические свойства","slug":"pharmacologic_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Комбинированный препарат. представляет собой комбинацию высокоактивных ферментов растительного и животного происхождения. оказывает иммуномодулирующее, противовоспалительное, фибринолитическое, противоотечное, антиагрегантное и вторичное анальгезирующее действие.вобэнзим оказывает положительное воздействие на ход воспалительного процесса, ограничивает патологические проявления аутоиммунных и иммунокомплексных процессов, положительно влияет на показатели иммунологической реактивности организма. стимулирует и регулирует функциональную активность моноцитов-макрофагов, естественных киллеров, стимулирует противоопухолевый иммунитет, цитотоксические т-лимфоциты, фагоцитарную активность клеток.под воздействием вобэнзима снижается количество циркулирующих иммунных комплексов и происходит выведение мембранных депозитов иммунных комплексов из тканей.вобэнзим уменьшает инфильтрацию интерстиция плазматическими клетками. повышает элиминацию белкового детрита и депозитов фибрина в зоне воспаления, ускоряет лизис токсических продуктов обмена веществ и отмирающих тканей, улучшает рассасывание гематом и отеков, нормализует проницаемость стенок сосудов.вобэнзим снижает концентрацию тромбоксана и агрегацию тромбоцитов. регулирует адгезию клеток крови, повышает способность эритроцитов изменять свою форму, регулируя их пластичность, нормализует число нормальных дискоцитов (тромбоцитов) и уменьшает общее число активированных форм тромбоцитов, нормализует вязкость крови, снижает общее число микроагрегантов, таким образом улучшая микроциркуляцию и реологические свойства крови, а также снабжение тканей кислородом и питательными веществами.вобэнзим нормализует липидный обмен, снижает синтез эндогенного холестерина, повышает содержание лпвп, снижает уровень атерогенных липидов, улучшает всасывание полиненасыщенных жирных кислот.вобэнзим повышает эффективность антибиотикотерапии, увеличивая концентрацию антибиотиков в плазме крови и очаге воспаления, а также уменьшает побочные эффекты антибиотиков (дисбактериоз).вобэнзим уменьшает выраженность побочных эффектов, связанных с приемом гормональных препаратов (в т.ч. гиперкоагуляцию).вобэнзим регулирует механизмы неспецифической защиты (выработка интерферонов), тем самым проявляя противовирусное и противомикробное действие."}}]},{"id":3,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Ревматоидный артрит, несуставный ревматизм, остеоартроз, болезнь Бехтерева, болезнь Шегрена, травмы (переломы, ушибы, дисторсии, вывихи, контузии), воспалительные процессы мягких тканей, хронические посттравматические процессы, травмы в спортивной медицине, посттравматические отеки, синусит, бронхит, бронхопневмония, панкреатит, язвенный колит, болезнь Крона, рассеянный склероз, ишемическая болезнь сердца, инфаркт миокарда, вторичная профилактика повторного инфаркта миокарда, тромбофлебиты, посттромботический синдром, васкулиты, облитерирующий тромбангиит, профилактика рецидивирующих флебитов, лимфатический отек, вторичный лимфатический отек, воспаление мочевыводящих путей (цистит, цистопиелит, простатит), хронические инфекции в гинекологии, аднексит, мастопатии."}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Индивидуальная гиперчувствительность к компонентам препарата. Тяжелые врожденные или приобретенные нарушения свертываемости крови (гемофилия, тяжелые поражения печени), заболевания, связанные с повышенной вероятностью кровотечений, тромбоцитопения."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"С осторожностью и под контролем врача следует назначать Вобэнзим при беременности и в период лактации."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Таблетки следует принимать внутрь, не менее чем за 30 минут до еды, не разжевывая, запивая водой (200 мл)."}},{"type":"paragraph","data":{"text":"Взрослые"}},{"type":"paragraph","data":{"text":"В зависимости от активности и тяжести заболевания Вобэнзим принимают в дозе от 3 до 10 таблеток 3 раза в день. В первые три дня приема препарата рекомендуемая доза составляет 3 таблетки 3 раза в день."}},{"type":"paragraph","data":{"text":"При средней активности заболевания Вобэнзим назначают в дозе 5-7 таблеток 3 раза в день в течение 2-х недель. В дальнейшем доза Вобэнзима должна быть снижена до 3-5 таблеток 3 раза в день, курс 2 недели."}},{"type":"paragraph","data":{"text":"При высокой активности заболевания Вобэнзим назначают в дозе 7-10 таблеток 3 раза в день в течение 2-3 недель. В дальнейшем, доза Вобэнзима снижается до 5 таблеток 3 раза в день, курс 2-3 месяца."}},{"type":"paragraph","data":{"text":"При хронических длительно текущих заболеваниях Вобэнзим может применяться по показаниям курсами от 3-х до 6-ти месяцев и более."}},{"type":"paragraph","data":{"text":"С целью повышения эффективности антибиотиков и профилактики дисбактериоза, Вобэнзим следует применять на протяжении всего курса антибиотикотерапии в дозе по 5 таблеток 3 раза в день. После прекращения курса антибиотиков для восстановления микрофлоры (биоценоза) кишечника Вобэнзим следует назначать по 3 таблетки 3 раза в день в течение 2-х недель."}},{"type":"paragraph","data":{"text":"В качестве терапии «прикрытия» во время проведения химио- и лучевой терапии, Вобэнзим следует применять в дозе по 5 таблеток 3 раза в день до завершения курса химио- и лучевой терапии; для предупреждения инфекционных осложнений, улучшения переносимости базисной терапии и повышения качества жизни."}},{"type":"paragraph","data":{"text":"При применении Вобэнзима с профилактической целью доза препарата составляет 3 таблетки 3 раза в день, курс 1,5 месяца с повторением 2-3 раза в год."}},{"type":"paragraph","data":{"text":"Дети"}},{"type":"paragraph","data":{"text":"Детям с 5-ти до 12 лет - на 6 кг веса ребенка 1 таблетка в сутки. С 12 лет по схеме для взрослых. Дозировка и длительность лечения зависят от тяжести заболевания и определяются врачом."}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Тошнота, незначительные изменения консистенции и запаха кала, аллергическая реакция, анафилактические реакции, рвота, временное ощущение переполненности желудка, метеоризм, диарея, эритема, зуд, гипергидроз."}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"О случаях передозировки препарата Вобэнзим не сообщалось."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"При одновременном приеме Вобэнзима с другими лекарствами случаи несовместимости не описаны."}}]},{"id":9,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Следует учитывать, что в начале лечения препаратом Вобэнзим возможно обострение симптомов заболевания. В таких случаях рекомендуют временно снизить дозу, лечение прерывать не следует. При инфекционно-воспалительных заболеваниях Вобэнзим не заменяет лечения антибиотиками, но повышает их эффективность. Вобэнзим не является допингом. Влияние на способность к вождению автотранспорта и управлению механизмамиПрепарат не оказывает негативного влияния на способность к вождению автомобиля и выполнению работ, требующих высокой скорости психомоторных реакций."}}]},{"id":16,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Препарат не оказывает отрицательного влияния на способность управлять транспортными средствами и выполнять работы, требующие высокой скорости психических и физических реакций."}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nТаблетки кишечнорастворимые, покрытые оболочкой."}},{"type":"paragraph","data":{"text":"По 20 таблеток в ПВХ/ПЭ/ПВДХ/алюминиевые блистеры."}},{"type":"paragraph","data":{"text":"По 2, 5 или 10 блистеров вместе с инструкцией по применению в пачку картонную."}},{"type":"paragraph","data":{"text":"По 800 таблеток во флаконы из полиэтилена высокой плотности. По 1 флакону вместе с инструкцией по применению в пачку картонную.\n\n"}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"\n\nПри температуре не выше 25 °C."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте!\n\n"}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"\n\n2 года."}},{"type":"paragraph","data":{"text":"Не применять по истечении срока годности\n\n"}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают без рецепта."}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nМукос Эмульсионс ГмбХ, Германия"}},{"type":"paragraph","data":{"text":"Мирауштрассе 17, 13509 Берлин, Германия\n\n"}}]},{"id":22,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"За дополнительной информацией обращаться в ООО «Атриум Инновейшенс РУС»:"}},{"type":"paragraph","data":{"text":"121059, г. Москва, ул. 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